Sentence examples for substantial backbone from inspiring English sources

Peptoids are poly N-substituted glycine)s with substantial backbone conformational flexibility.

Initial genomic studies revealed that R. solanacearum strains have a substantial backbone of common housekeeping and virulence functions, but also carry a divergent set of genomic modules that likely confer distinct ecological phenotypes and host specificity [ 19, 24].

Tony Blair showed real backbone last week.

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Unlike worms, they also have strong backbones.

The structure of the Gln193Arg/His194Thr mutant revealed no substantial changes in the backbone of the enzyme or orientation of side chains resulting from mutation.

Fitted candidate loops with RMSD a > 5.0 Å are automatically rejected, since they likely require a substantial change in their backbone conformation to fit into the target site.

As illustrated in Figure 3E, notable differences are observed between wild-type and mutant HgD: the Cα atoms of His22 and Thr23 in P23T HgD are displaced by 0.6 and 0.5 Å from the positions in the wild-type protein, respectively, and substantial changes in the backbone dihedral angles are present.

This substantial difference substantiates the existence of strong coupling between the molecular polarizability and the backbone conformation in the polysilanes.

The backbone of this substantial system is the NIF Registry, a semantically enhanced catalog of over 4500 biologically relevant web resources.

Data to date suggest that β anomers exhibit substantial steric effects near the backbone, similar to β-branched and aromatic amino acids, whereas α anomers are more compatible with compact protein conformations.