Sentence examples for substantial antagonist from inspiring English sources

It's terrific that in this last run of episodes, the SC&P gang has had a substantial antagonist in the form of a man who tells you everything is going to be fine so smoothly that you instantly reach for your wallet and your soul to make sure both are still in your possession.

Moreover, since the frequency in the present study ranged between 18 and 36 Hz, a harmonic reflectory response of the involved muscles seems plausible [17] as well as a substantial relaxation of the antagonist [23].

Studies with both agonists and antagonists indicate substantial yet submaximal receptor activation by endogenous adenosine during ischemia [27] supporting the possibility of reduced receptor reserve in ischemic myocardium.

There is substantial evidence that agonists and antagonists induce different conformational changes in the region of the C-loop with agonists causing C-loop closure around the bound ligand.

After loratidine became available as an over-the-counter medication, Sullivan et al [ 54] found that prescriptions decreased for both antihistamines and the total category of allergic rhinitis medications (including inhaled corticosteroids and leukotriene receptor antagonists) with a substantial reduction in pharmacy costs for these medications.

Stratified analysis of current, recent and past exposure, as well as periods of no vitamin K antagonist (VKA) use, showing substantial differences in comorbidities and outcome events.

The macaque studies have also demonstrated that the use of an oral CCR5 antagonist, CMPD167, can protect a substantial portion of macaques from infection with a CCR5-using SHIV virus.

Conclusion: Use of β-adrenergic antagonists was associated with a substantial reduction in the incidence of postoperative neurologic complications.

CONCLUSION: Use of beta-adrenergic antagonists was associated with a substantial reduction in the incidence of postoperative neurologic complications.

Different mechanisms of action for the agonists and antagonists are supported by a substantial body of published work.

In the majority of the elderly population with OAB, a muscarinic receptor antagonist should be able to provide substantial relief from the symptoms of OAB, with a minimal side effect profile.