Sentence examples for substantial and direct from inspiring English sources
The emphasis is toward CO2/CH4 separation, considering its substantial and direct relevance to the gas industry.
The morbidity after failed treatment of an infected revision arthroplasty is substantial, and direct exchange should be considered only in centres which deal with revision arthroplasty frequently.
These data indicate that phosphorylation of SIN1 T86 results in a substantial and direct activation of mTORC2 kinase activity.
This review has shown that migration of health workers is a phenomenon in which decisions and actions taken in one country can have substantial and direct effects on another country.
While the (female) participants in this study provided vivid descriptions of unsafe sex linked to their own alcohol use, it is probable that alcohol use by men is also making a substantial and direct contribution to the occurrence of unsafe sex and sexual violence, and therefore a contribution to the prevalence of HIV and other STIs in these two states.
The cost and healthcare burden associated with trichomoniasis are substantial, and the direct medical costs are conservatively estimated to be $24 million per year in the United States.
This burden includes increased disease risk, impaired HRQoL, and substantial direct and indirect costs.
Across the NeP conditions, subjects showed high pain levels which were associated with a higher comorbidity burden, increased HRU including medication use for NeP, greater loss of productivity due to NeP, and substantial direct and indirect costs.
Sepsis is a systemic response to infection associated with significant mortality and substantial direct patient care costs [ 1].
Treatment efficacy is important to establish for these symptoms because combined they account for a considerable amount of disability and substantial associated direct and indirect costs to society.
Thus, the economic burden of IBS in the United States is substantial and includes estimated direct costs (eg, physician visits) of $1.7 to $10 billion annually and estimated indirect costs (eg, employee absenteeism) of up to $20 billion annually [ 7].
