Sentence examples for substantial amount of variants from inspiring English sources

First, we removed substantial amount of variants from our analysis.

The mismatches allowed between the hexamer primers and the RNA templates resulted in substantial amount of false variants (Fig. 1 of the Supplementary Material); (ii) distance to the exon intron boundary (DJ); and (iii) the uniqueness of the read mapping in the genome and transcriptome (ED).

Thus, our initial interpretation of a negative element mapping to hPLP1 intron 1 positions 1685 to 3168 may be incorrect if 2.7hPLPZ produces a substantial amount of the splice variant containing exon AB in its entirety.

The GoNL trio design allows calling a substantial amount of de novo variation (both SNPs and structural variants).

However, it is becoming increasingly apparent that a substantial amount of the phenotypic variation within populations is attributable to rare genomic variants [ 2] and the haplotypes on which these variants lie cannot be reliably inferred from genotypes at common marker single nucleotide polymorphisms (SNP).

Site assignment of methionine oxidation using this workflow has two major drawbacks: (1) a substantial amount of sample is required to allow variant fractionation and subsequent peptide mapping (especially for low abundant variants) and (2) the procedure is time consuming, due to elongated sample preparation and LC-MS analysis.

This is due to the fact that, within each species, the splice variants share a substantial amount of sequence identity.

Third, the trio design of the project in combination with the medium coverage of each genome allows estimation of haplotypes accurately, and to call a substantial amount of the more rare and de novo variation (both SNPs and structural variants).

The polygenic model of inheritance, in which each variant contributes a small risk in many individuals, is often invoked to account for a substantial amount of the population attributable risk (PAR) (Dragani et al, 1996; Fletcher and Houlston, 2010).

Gilder has done a substantial amount of both.

I have spent a substantial amount of money in development.