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Although much enthusiasm initially surrounded the profiling studies from van 't Veer and others, a substantial amount of skepticism has since emerged in the breast cancer community regarding whether gene signatures predictive of breast cancer outcome will eventually be incorporated into clinical breast cancer decision making.
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Hill faced a significant amount of skepticism.
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I have spent a substantial amount of money in development.
The foundation lost a substantial amount of money.
"He had a substantial amount of inflammation," Tellem said.
And noise complaints usually involve a substantial amount of subjectivity".
A substantial amount of their business is illegal.
A substantial amount of England's forestland is privately owned.
"There is still a substantial amount of uncertainty".
A substantial amount of nucleosynthesis must have occurred in stars.
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