Following the work by Sørlie and colleagues that presented the intrinsic molecular subgroups of BC based on gene expression patterns, a substantial amount of information has elucidated the complexity in pathways driving the different BC subgroups.
A substantial amount of evidence has demonstrated that AS complexity is relevant to eukaryotic evolution, development, adaptation, and complexity.
However, computational methods that can handle the complexity (noisy, substantial amount of variables, high dimensionality, etc). of these biological data are often unavailable [ 1].
A substantial amount of attention has focused recently on the complexity of the food safety system in the United States, which includes a huge number of agencies, sometimes overlapping programs, databases and legal authority, and the inevitable consequence of inefficient and confusing communication.
Not only is a substantial amount of energy is required for cooperation, the accompanied increase of complexity may be substantial as well.
#7 Nuance and Technical Complexity in Street Art Banksy's work is so often thought-provoking and/or requires a substantial amount of technical skill (outside of just being able to paint).
By applying models of varying complexity in atmospheric and orbital dynamics, previous studies have found that Earth-like planets on circumbinary orbits may indeed be capable of sustaining liquid water on their surface for a substantial amount of time4,5,6,7,8,9,10,11.
Gilder has done a substantial amount of both.
I have spent a substantial amount of money in development.
The foundation lost a substantial amount of money.
"He had a substantial amount of inflammation," Tellem said.
