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In case of the ChG/nHaP scaffolds, we have observed a substantial amount of cell attachment and cell spreading.
The higher dose of CK2 inhibition even causes substantial amount of cell death, as revealed from the distinct increase in sub-G0/G1 cell population.
Once a substantial amount of cell necrosis has occurred, organ function recovery is not always possible, even when adequate VO2 is restored.
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We observed that all the mannosylated recombinant OVA antigens showed a substantial amount of cell-associated fluorescence after 90 min which was inhibited by the addition of YMs.
Such protocols are only successful if fresh tissue from early developmental stages is used and even here a substantial amount of cells do not survive the procedure.
Under similar conditions, butein was found to induce substantial amounts of cell death at a concentration of 10 μM only.
Analyses have shown that cellularly complex targets lead to averaged gene expression profiles that lack substantial amounts of cell type specific information [ 23].
Toxins or substantial amounts of cell wall degrading enzymes are likely not involved in the Pythium-rice interaction, because pathogen invasion was not associated with extensive tissue damage and was not preceded by cell death.
Existing methods to study proteins associated with a given RNA are laborious and require substantial amounts of cell-derived starting material.
In this regard, it may provide a complement to biotin-labeled RNA pull-down/mass spectrometry-based approaches, which have proven successful in identifying RNA binding proteins [ 8] but require substantial amounts of cell-derived starting material and are laborious and time-consuming.
In contrast, PC3 cells have to be treated for up to 48 h before a substantial amount of apoptotic cell death can be detected.
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