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In this mini-review, we focused on substantial advances of 3D bioengineering technologies for the regeneration of complex oral organs with the reconstruction of 3D bioengineered organ germ using organ-inductive potential embryo-derived epithelial and mesenchymal cells.
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These results represent a substantial advance of our understanding of how ribosomes function.
Despite these limitations, we found several promising strategies that may contribute substantial advances to the study of health outcomes in patients with rare diseases.
In her presentation 'Measuring Disease Activity and Severity in Clinical Trials and the Clinic: Same or Different?' Dr Petri discusses the revised clinical and immunologic criteria for the classification of SLE, necessitated by substantial advances in knowledge of immunologic interplay of SLE.
However, the analysis clearly points out that the development of well-designed urban patterns, oriented to receive transit services, is not sufficient, by itself, to produce substantial advances in terms of sustainability of transport system.
158, 159 GISTs receive today considerable attention because of substantial advances in the understanding of their pathogenesis and development of efficient targeted therapies.
Although for many of these we remain some distance from a complete enumeration of causal mechanisms, there have already been substantial advances in understanding of disease - the role of autophagy in inflammatory bowel disease [ 4] and cell adhesion in autism [ 5, 6], for instance.
These increases in population-based survival rates reflect the substantial advances in treatment of a wide range of childhood cancers since 1970.
Although all of these approaches have made substantial advances in our understanding of the function of many proteins, a lack of specificity or restricted applicability has limited their utility.
In parallel, there have been substantial advances in terms of concepts, methods, and techniques for the study of dynamic systems, advances that have originated in the control and systems theory.
In recent years animal models and neuroimaging of tinnitus perception have contributed to substantial advances in the understanding of the pathophysiology of tinnitus [ 2, 6- 8], which in turn has prompted the development of new treatment strategies [ 4, 9- 11].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com