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In general, the results suggest that increasing IU is associated with increasingly risk adverse behaviors; however, the relationship appears complex and in need of substantial additional research to understand how clinically-significant IU would impact pathology-related behaviours.
In addition to the need for larger validation studies to confirm the observed associations, substantial additional research is needed to understand the functional impact of the various candidate polymorphisms on protein function and expression levels and how these functional changes contribute to alterations in ARDS outcomes.
Specific recommendations regarding individual supplements and their dosing require substantial additional research.
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However, substantial additional basic research is needed to develop a cell therapy product based on hPSC, and in this setting the collaboration between academia and industry is important.
Large knowledge gaps remain, resulting in a substantial need for additional research to improve our understanding of how weather and climate, both directly and indirectly, can influence human health.
But today's record federal deficit, along with the demands of homeland security in the era of terrorism, and of food safety in the era of mad cow disease, do not augur well for hopes that Congress will come up with any substantial additional funding in other research fields.
Economic research suggests that societal gains from investment in research have been enormous and advances that result in even modest reductions in cancer mortality would more than justify substantial additional investments in biomedical research [64].
Moreover, there remains substantial value in performing additional research, identifying improved methods of antemortem testing.
The authors believe that additional research and substantial efforts are needed to standardize the terminology of benign (and malignant) melanocytic neoplasms.
More sophisticated enhancements, such as audio and video components, might require more substantial faculty development efforts, and additional research is needed on both how to better disseminate these curricula, and on practice and patient-level outcomes.
After asking about our health, he began to walk through his thoughts on my latest research project — and gave me substantial additional work to do, with a pretty short timeline.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com