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While fully standardized methods may be a research ideal, local circumstances may require substantial adaptation of the methods to achieve meaningful local representation.
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Whole genome comparison of Sii CJ18 to Sii ATCC BAA-102T and related streptococci revealed substantial adaptations to the dairy environment in CJ18, paralleling that of S. thermophilus.
This conjunction of problem attributes and context in which experiments and learning takes place can create substantial adaptation demands.
Therefore, it has been suggested that, unless there is substantial thermal adaptation of coral hosts and/or their associated symbionts [11], [12], large scale bleaching and mortality events could occur annually on the world's coral reefs by 2050 [13].
However, these accounts ignore substantial adaptations in motor behaviour that accompany absence or loss of a limb, which could be powerful drivers for plasticity (Scholz et al., 2009).
This led to substantial adaptations, mainly to simplify and clarify the questions, which were also discussed with the authors of the PACIC.
A comparison of the female and male results suggests that substantial sex-specific adaptation of gene expression levels has occurred following the out-of-Africa migration of D. melanogaster.
Substantial variation exists in the adaptation of parents and families of children with perinatal stroke, even among children with moderate and severe conditions [ 3].
Advances in genomics and population genetics have led to substantial progress in identifying local genetic adaptation of livestock species.
This will require the adaptation of the existing equipment, raising substantial technological and image analysis challenges.
The performance of the designed consortium was poor, and the results implied that bioleaching consortia (mesophiles or moderate thermophiles) cannot be assembled 'off-the-shelf', at least not without a substantial period of adaptation.
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