Sentence examples for substantial activation from inspiring English sources

We found that anti-GD2 antibodies did not cause substantial activation of caspase-3: the level of activity of this effector caspase was 3 4 folds lower for anti-GD2-treated cells when compared to the EL-4 cells treated with staurosporine.

More direct studies of NF- κB activation revealed that Jurkat cells exposed to rhTRAIL did activate NF- κB. Figure 4 shows a substantial activation of NF- κB, 30 min following addition of rhTRAIL to the cells, although this activation was less pronounced than that caused by treatment with the strong NF- κB activator, TNF- α.

These multiple inputs make them most likely candidates for accumulating substantial activation if all neurons are equally subject to noncorrelated spontaneous activity ("noise", Garagnani and Pulvermüller 2013).

Surprisingly, the substantial activation of the phaG gene was observed.

Results showed substantial activation overlap between speech and non-speech function in regions.

Substantial activation was still maintained upon inversion of the fragment relative to the promoter (Fig. 5B).

Dopamine neurons showed substantial activations to unrewarded stimuli and their conditioned stimuli in highly rewarded contexts.

Osteoprotegerin, and antibodies directed to the ligand or the receptor activator of nuclear factor-κB, have demonstrated substantial activity in inhibiting osteoclast activation, recruitment and differentiation.

This mechanism could explain how the brain circuits provide substantial background activation of NMDARs while maintaining a negligible ambient glutamate level in the extracellular space.

Using customized engineered TALEs, a substantial transcription activation and viral outgrowth was achieved with cells obtained from different HIV-1 patients.

Acquired resistance resulted in substantial AKT activation and upregulation of MCL-1 and BCL-xL levels that sequestered BIM.