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Subjects with histories of head injury, otological disease, other diseases that could affect hearing, and previous or present treatment with ototoxic substances were excluded.
Patients admitted with severe disturbances, such as cardiogenic shock or pulmonary edema, and patients with chronic obstructive pulmonary disease, stroke, cancer, and mental disorders, as well as patients addicted to alcohol and other psychoactive substances, were excluded from the study.
When comparing the data of the paired tissue group in which 10 tissue RNA samples with high inhibitory substances were excluded, a higher stability of each gene, and a higher similarity between the two algorithms became evident (Table 4; Figure 4), indicating that the existence of qRT-PCR inhibitors in RNA samples can increase the variation of qRT-PCR assay.
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However, food, drugs, cosmetics, pesticides and other substances are excluded from regulation under TSCA.
Participants with uncontrolled mixed substance abuse, acute alcohol abuse, or acute axis I psychiatric morbidity according to Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) not related to substance were excluded.
Among the 88 patients with neither excessive alcohol nor cannabis use, three patients had excessive use of other substances, which were excluded from the bivariate analyses.
Individuals with substance abuse were excluded because of the potential impact of substance abuse on the experience of stigma.
Subjects with current alcohol or substance misuse were excluded.
Women with a history of thyroid disease, any medical illness, depression or substance abuse were excluded.
Mothers with psychotic disorders, manic depression and/or substance dependence were excluded from the study.
Psychoses, bipolar affective disorders and mental disorders caused by psychoactive substance use were excluded.
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