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Calcium-blocking properties of the substances were evaluated.
The anti-HIV 1 activities of these substances were evaluated in PM-1 cells, using Indinavir® as standard (IC50=0.2 μM).
The response in terms of nitrogen metabolism, antioxidant enzyme activities, contents of ROS and osmoregulation substances were evaluated in order to evaluate the role of Spd in promoting tomato plants tolerance to saline-alkaline stress.
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However, conclusion on ACRs is flawed as experimental data on chronic fish toxicity are still limited with less than 40 substances being evaluated [2, 12, 23], or as most evaluations included substances such as pesticides that are expected to exert specific biological effects [6, 12, 22].
In this study, the determination of OH-radical and ozone exposure from second order rate kinetics with two internal tracer substances was evaluated as alternative approach for these waters.
In 2012, 36 substances are evaluated.
The BPR provisions will also apply to existing active substances being evaluated under the BPD review program.
The consumption of five substances was evaluated by analysing wastewater from 19 European cities for a 1-week period in 2011 24.
During this period, the appearance of inflammatory reactions (edema and/or erythematic areas) or any other toxic reactions due to the substances was evaluated.
When a TDS does not contain suspended API, but rather, dissolved API, it is recommended that the potential of formation of crystals during storage (e.g., due to change of crystal form of the amorphous drug substances) be evaluated during product development.
Two methods, prescribed in USP, for the analysis of related substances of valganciclovir hydrochloride drug substance, were evaluated in terms of selectivity and ease of use.
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