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The responses to different substances differ in both sensitivity (dose-response curve shifted sideways) and saturation (maximum response).
Although the substances differ in their properties, uses, exposure pathways and regulatory consequences, the outcome of a PBT/vPvB assessment should not depend on the framework under which they are evaluated, since the protection goals do not differ.
Both substances differ in their hydrophilic character: AlPCS4 is hydrophilic per se; PVP-hypericin is made water soluble by the addition of polyvinylpyrrolidone to hypericin [ 13], resulting in a different behavior at the higher concentrations employed.
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ZONE centrifugation through sucrose density gradients is widely used for the separation of substances differing in their sedimentation behaviour, and has been applied to viruses, ribosomes and proteins.
If the physico-chemical characteristics of different nanoforms of the same substance differ in a relevant manner, they have to be considered separately for the further test performance and REACH requirements.
If the physico-chemical characteristics of different nanoforms of the same substance differ in a relevant manner they have to be considered separately for further test performance and REACH requirements.
Reactions of irreversibly adsorbed and dissolved substance differ in their equilibrium redox potentials and in the functional dependence of the peak current on the potential sweep rate.
If nanoforms of a substance differ in a relevant way, information requirements have to be fulfilled separately for the individual forms.
Substances differ widely in the likelihood that they will crystallize under conditions in which the crystalline state is the inherently stable one; glycerol is a well-known example of a compound prone to supercooling.
Large cells that form by fusion in reaction to the presence in the body of foreign substances differ from Langhans giant cells in that their many nuclei are scattered throughout the cell.
The types of graphite-like substances include filamentous,(4) fluffy, and firm or solid graphite;(22) these substances differ from one another in a variety of traits such as color, hardness, texture, SEM, FT-IR, Raman, and XRD spectra.
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CEO of Professional Science Editing for Scientists @ prosciediting.com