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All the components take part in this process: there is just as much tendency for the solvent to diffuse from regions where its concentration is high (and the solution is therefore dilute) to regions where its concentration is low (and the solution is concentrated) as there is for the dissolved substance to diffuse from regions where it is concentrated to those where it is dilute.
In most approaches, LA are applied to a larger area within the nasal cavity and therefore the concentration would have to be high to allow enough substance to diffuse close to the SPG.
Similar(58)
During FET tests the substances have to diffuse into the developing embryo.
As a substance, nicotine is able to diffuse rapidly into various organs and tissues.
While it appears reasonable to posit that a substance will reach the SPG with an image-guided injection, the ability of a substance to passively diffuse and reach the SPG after intranasal application is uncertain.
After solidification, the paper disks were placed on the inoculated agar plates and allowed to diffuse the loaded substances into refrigerator at 4 °C for 2 h to allow the diffusion of substances.
According to this special property, researchers have reported extensively the use of scCO2 to diffuse some polar substances into a polymer matrix such as PP to modify its physical and chemical properties [20, 21, 22].
SD releases noxious substances with increased blood flow thought to diffuse outward.
NO is a gaseous molecule that is able to diffuse deeply into tissues; indeed, such a substance has been shown to regulate cell behaviors in many ways, including the relaxation of vascular smooth muscle [ 3, 32].
Tissue poses some diffusion barrier as a function of molecular weight and size; in our preparation the 37 amino acid large CGRP molecule can be expected to diffuse slower than the solutions containing the pharmacological substances.
After the cells were warmed to 37 °C for 5 min, agonist (isoproterenol for SNAP-β2ADR or Substance P SNAP-tag-NK1R) for was added to the media and allowed to diffuse through the solution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com