Sentence examples for substance preparation from inspiring English sources

Are nanomaterial test substance preparation and characterization sufficiently standardized to ensure reproducibility of test results in accordance with specified parameters?

Further investigations, however, are necessary to develop and assess standardized procedures for test substance preparation for oral administration ensuring reliable substance homogeneity.

Evidently, also homogeneity of the test substance preparations influences NM uptake upon oral delivery.

Test substance preparations were produced daily and were kept homogenous until administration by continuous stirring with a magnetic stirrer.

Also BaSO4 was not distributed homogeneously in the test substance preparations, and only contained an average of 6.5 g BaSO4 per 100 g (Table  2).

The test substance preparations were administered daily by gavage over a period of 4 weeks to groups of 5 male and 5 female rats.

For this purpose, three separate samples of the test substance preparations were taken from the bottom, middle, and top layers of the vials (which would necessarily have the same test substance concentrations in homogenous suspensions).

Whereas homogeneity of the test substance preparations was satisfactory in the surface-functionalized SiO2 and ZrO2 NMs, the non-surface-functionalized SiO2·naked and the powder BaSO4 were not distributed homogeneously.

Likewise, further investigations should aim at determining the amount of NM that can enter the body upon ingestion under different experimental conditions taking into account a variety of different test substance preparations.

Since NMs can agglomerate and sediment quickly in suspensions and this can considerably affect the final, effective dosage reaching the target organism, it is essential to assess the homogeneity of test substances and to verify the effective concentration in the test substance preparations.

specific gravity In interpreting the relevance of these observations for human safety assessment, a number of issues have to be taken into account: (1) Do the physico-chemical characteristics of the nanomaterials in the test substance preparations reflect those of the same NMs as they would enter the human body?