Nevertheless, LRTP is not included explicitly, although substances may represent an environmental hazard to the intrinsic value of sensitive remote regions as highlighted in the Guidance for the implementation of REACH.
Still, some well-studied substances may represent an important scientific paradigm or useful reference, thereby justifying their inclusion in some research studies.
It has been suggested that enhanced release of glutamate and other substances may represent an early event in a number of, if not all, neurodegenerative diseases (e.g., [ 29]).
Although we translated only the first 250 CAS numbers into common names in order to exclude other commonly covered substances, such as hydrogen, glutathione, and P450 enzymes from consideration, the findings suggest that the top-100 substances may represent about one-third of the total number of links.
From further experiments, Bence Jones deduced its physical properties and determined that it was different from albumin; however, from its chemical composition, he presumed it to be a 'deutoxide of albumin' and suggested that this substance may be represented by C48, H38, N6,O18 or by C40, H31, N5,O15.
28 Some suggest that the comorbidity of PTSD with substance abuse may represent a shared genetically mediated vulnerability to psychopathology after trauma exposure.
Our population of 16 to 20 year old Irish male young offenders cannot be directly compared but our finding of the UHR state in 23% associated with impairments of function and multiple substance misuse may represent a further developmental step on the way to the emergence of a severe and enduring psychosis in some of that 23%.
Substance may be a different issue.
The argument for substance may be criticized on several grounds.
The measurement objects are also connected to substance objects, indicating the measured substance, e.g. an image may represent the 2D distribution of a metabolite.
