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The drug substance is formulated to the final drug product using the same drug product formulation as the originator.
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The MAb1 drug substance was formulated at 150 mg/ml in 20 mM histidine hydrochloride, 200 mM arginine hydrochloride, 0.04% polysorbate 20 at pH 6.0 and stored at −70°C in polyethylene terephtalate bottles.
Based on the Gibbs-Thomson condition, a complete mathematical model describing the dendritic growth problem for pure substances is formulated.
Desensitizing toothpaste is formulated to coat the teeth and shield them from the substances that cause them to feel sensitive and painful.
A party line is formulated and chosen.
Next, the proposed DPC method is formulated.
Mucoadhesive substances have been formulated to block the medication at the sublingual level [ 22].
The second attempt, sponsored by the Valley Fever Vaccine Project, a community effort similar to the one that led to the Salk polio vaccine, yielded a substance that couldn't be formulated to F.D.A. standards.
The union is formulating its own proposal.
A microbicide is any substance that kills germs, and it can be formulated as a cream, gel, film or suppository.
The duchess, as Hilary Mantel has brilliantly argued, looks as if she has been formulated from some secret substance for this particular brand of public life, perfect wife and perfect mother.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com