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The aim of this study was therefore to determine strategies for controlling drug substance characteristics pre and post-crystallisation to facilitate the production of micronised SS with desirable particle attributes for optimal delivery as an inhaled aerosol.
BioRAM considers the therapeutic target with the drug substance characteristics and enables collection of critical knowledge for development of a dosage form that can perform consistently for meeting the patient's needs.
Rather, the technology platform (i.e., dry blend versus wet granulation) should be considered along with the drug substance characteristics, level of excipient in the composition, as well as drug load.
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Electron microscopy revealed the formation of double- or multi-membrane-bound structures containing recognizable cellular organelles and high electron density substance, characteristic of autophagosomes and autolysosomes, in PL-treated U2OS cells.
There are also special tests based on the presence in the blood of substances characteristic of specific infections, such as the serological tests for syphilis, hepatitis, and human immunodeficiency virus (HIV; the AIDS virus).
Designed for in the field use, the handheld device can distinguish substances characteristic of a certain wine variety.
By electron microscopy, cells overexpressing EIG121 had abundant double- or multimembrane-bound structures containing recognizable cellular organelles and electron-dense substances characteristic of autophagosomes and autolysosomes.
This study examined sociodemographic, tobacco-related, and substance use characteristics of poly-tobacco use compared to mono-tobacco use among youth and young adults (12 34 years) in the United States.
(2) To identify substances commonly smoked in hookahs and other substance use characteristics of hookah smokers.
Demographic, birth and substance exposure characteristics were investigated for statistical significance using Fisher's exact test.
This study analysed poisoning incidents in Korea from 2005 to 2009, by age and gender, causative substance, and characteristics.
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