One of the high IL-10 producing subsets is the CD1dhiCD5+ B cell subset, termed "B10 cells" by Yanaba and Tedder [6].
Accordingly, the total microtubule-related kinase subset (termed "kinome") is distinct in animals and plants.
Recently, a distinct Th-cell subset termed TFH and characterized by elevated expression levels of multiple surface proteins and BCL-6 as well as enhanced IL-21 secretion, have been identified as true helper cells for antibody responses.
In recent years, a distinct T-cell subset, termed Th17 cells, has also been identified and seems to play key roles in the activation of neutrophils and immunity to bacteria, particularly at mucosal surfaces.
The group of poorly conserved miRNAs identified in this study includes a subset termed as bovine specific miRNAs, which represent miRNAs with a seed sequence unique to Bos taurus.
One subset, termed Th17 cells, was first shown to develop from naïve precursors under the influence of transforming growth factor β (TGF-β) and IL-6 ± IL-1 and to depend on IL-23 for expansion and survival.
This classical paradigm was maintained until 2005, when a distinct lineage of proinflammatory Th cell subsets, termed Th17 cells, was identified [ 16, 17].
Of note, blood monocytes consist of two principal subsets, termed 'classical' and 'non-classical' monocytes, which are characterized by the expression of CD14++ or CD14+CD16+, respectively [ 26].
Tensor ID selects, for a user-defined accuracy ϵ, a near optimal subset of terms of a CTD to represent the remaining terms via a linear combination of the selected terms.
Revigo was used to reduce the GO term redundancy to give a representative subset of terms (Supek et al., 2011 ).
