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Subsequently, we calculated the significance of these differences using Student's t test.
Subsequently, we calculated the free energy profile along the identified ion permeation path for a single Na+ ion using umbrella sampling (US) (see Supplementary Materials for details).
Subsequently, we calculated the principal components of the gene expression profiles, retaining the first 5 PC in each analysis as documented in the text.
Subsequently we calculated the weighted average IBS over all loci, and finally corrected for the population average IBS to obtain a mean relatedness equal to zero.
Subsequently, we calculated the geometric means for the filtered genes and applied one class SAM (Significance Analysis of Microarrays) analysis to identify the differentially expressed genes by grading each gene using a modified t test [20].
Subsequently, we calculated the AUC values for each quartile.
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Subsequently, we calculate the market share for the considered hospital system and its competitors.
Subsequently, we calculate the score without considering the health factors (see Additional file 4).
Subsequently, we calculate the root-mean-square (RMS) amplitude in a moving time window with a duration of 4/f for each frequency band.
Subsequently, we calculate the Normalized Hamming Distance (NHD) between the vector of proteins in one entry of the matrix and the corresponding vector for S. cerevisiae from that same column.
Thus, in order to compare all agents we calculated the NCB for each one of the 1000 simulations and subsequently we calculated for each agent the proportion of the simulated trials in which each agent had the highest NCB across a range of RBAT values.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com