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Earlier results have shown that EGCG, chief constituents of green tea, was observed subsequently to inhibit nuclear translocation and protein expression of AR in a tumor xenograft model [ 63].
Activation of these MAPK results in nuclear translocation and activation of NF-κB and subsequently to transcription of the target genes, including adhesion molecules and pro-inflammatory cytokines.
In vertebrates, binding of dioxin to Ahr triggers its translocation from the cytoplasm to the nucleus, followed by binding to nuclear Arnt and subsequently to XRE sequences [8] (Figure 1A).
Thus, our results suggest that PUMA up-regulation and subsequently Bax translocation appear to contribute to E2F-1-induced apoptotic pathway.
We found that conformational dynamics of ribosomal PRE-translocation (PRE) complexes prior to translocation were also affected by Onc112.
Published MLL translocation frequencies report a high level of translocation t(4 11) compared to translocation t(11 19).
Subsequently, the translocation channel is believed to extend to the target cell membrane to facilitate substrate translocation (Christie et al., 2005).
Subsequently, the translocation of AtgH GFP to the vacuole upon carbon starvation in the ΔatmA background was evaluated.
For S100A9 and S100A12, phosphorylation of at least two different amino acids was shown to induce augmented calcium binding, which subsequently led to plasma membrane translocation of the proteins [ 44].
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This data suggested that SNE stimulated PKC ζ and subsequently induced translocation of p-PKC ζ into the plasma membrane, leading to improved functional rOa3 transport under T2DM condition).
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