Lastly, we found reduced RGC numbers in Nf1+/−GFAPCKO mice, supporting a model in which the combination of optic nerve Nf1 heterozygosity and glial cell Nf1 loss results in disrupted axonal-glial relationships, subsequently culminating in the degeneration of optic nerve axons and loss of their parent RGC neurons.
When the Ionians revolted in 499, all the kingdoms of Cyprus except Amathus joined them; the revolt was subsequently suppressed, culminating in sieges of Paphos and Soli.
However, the movement has recently nominated a new leader, Ali Salem al-Bidh, an ex-Marxist who led South Yemen into unity with the north in 1990 and subsequently led the attempted breakaway which culminated in the 1994 civil war.
In 1998, doomed Doncaster fell out of the League after an appalling season that culminated in then chairman Ken Richardson attempting to burn down the main stand at Belle Vue, and subsequently going to prison.
This sparked a manhunt, which culminated in Guzmán's arrest (and, subsequently, his first prison escape).
What Hedren subsequently endured in the making of The Birds – cruelties which culminated in her having live seagulls and crows thrown at her in an attic for five consecutive days of filming – have long been an open secret in Hollywood.
He walked out of Radio 1 in 1997 after going on a 17-hour pub crawl, and was subsequently fired from Virgin radio in 2001, an episode which culminated in a High Court judge calling him "a petulant prima donna of overbearing arrogance and conceit, as well as a liar".
The Russian threat culminated in the 1768 74 war with Turkey, and the Russians subsequently claimed the right to exercise a protectorate over all the Orthodox Christians of the Ottoman Empire on the basis of their interpretation of the terms of the peace settlement with the Ottoman Empire by the Treaty of Küçük Kaynarca.
Subsequently, the Mexican government put forward a series of market reforms that culminated with the implementation of the North American Free Trade Agreement in 1994.
However, his preference for Nelson over the more senior admirals Sir William Parker and Sir John Orde provoked a storm of protest, which eventually culminated in Orde challenging St Vincent to a duel, and being subsequently ordered to return to Britain.
