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Drugs granted orphan drug designation at the time of original approval were subsequently approved for 77 supplemental indications, 40 (52%) of which were indications not related to rare diseases.
Mr. Foster, 43, one of 300 people who attended, met with a representative of his mortgage holder and was subsequently approved for a loan modification.
Retinoids are topical prescription drugs that were originally approved for treating acne (Retin-A), and subsequently approved for treating photodamaged skin, including fine lines and wrinkles.
While this could mean that the buyer will have to pay certain processing costs even if he is not subsequently approved for a mortgage, it might be wise to take that chance.
Asfotase alfa was granted breakthrough therapy designation and subsequently approved for the treatment of hypophosphatasia (HPP; a genetic metabolic musculoskeletal disorder) and is used in this discussion to illustrate COA selection in a pediatric rare disease.
As they used to tell me when I was over there was 'Women zhongguo ye you zhengzhi' — 'We have politics too in China.' " Mr. Huntsman said he was subsequently approved for entry to attend a board meeting in China.
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His defense rested on arguments he made earlier that he had been directed by ethics officials to arrange for Ms. Riza's compensation only after he had tried to avoid involvement, and that officials subsequently approved of what he had done.
In February, US President Donald Trump proposed cancelling WFIRST, although Congress subsequently approved funding for it.
"It was Kevin Thelwell who was responsible for creating the initial list of prospective candidates, which was subsequently approved by me for 'sieving or filtering' prior to interview.
RESULTS: Small multidisciplinary groups and a consensus panel, using a nominal group technique, modified and subsequently approved computable algorithms for fatigue, dyspnea, moderate pain, severe pain, depression, and anxiety.
48 Lenvatinib was subsequently approved in 2015 for patients with progressive, RAI-refractory DTC.
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CEO of Professional Science Editing for Scientists @ prosciediting.com