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Natural and human-induced disturbances modify the stand age and succession dynamics of the landscape in a unique way, changing the live biomass and dead organic matter stocks and subsequent turnover [65, 66].
It is a scenario that is reminiscent of the "taxon pulses" proposed by Erwin [27], [28] to explain the geographic expansion and subsequent turnover of clades through time [also see 29], [30].
This reorganization involves F-actin assembly from soluble monomers in the cytoplasm and their subsequent turnover through depolymerization to replenish the precursor pool [ 2].
10 Due to this high affinity, the binding to the target and subsequent turnover of the drug target complex can contribute significantly to the disposition of biologics.
Thus the observed increase in polyadenylated plastid messages late in the recovery from N-starvation may reflect a subsequent turnover of messages.
Reversible post-translational modifications (PTMs) of proteins through addition and removal of molecular moieties are essential in exerting rapid changes to external stimuli without the input of transcription, protein synthesis, and subsequent turnover of messenger RNA and protein.
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After that public relations debacle, the subsequent turnovers were handled more discreetly.
Pre-steady state kinetic (rapid-quench) analysis of hcSHMT showed burst kinetics, indicating that glycine formation occurs fastest in the first turnover relative to the subsequent turnovers i.e. glycine release is the rate-limiting step in the hcSHMT reaction.
Subsequent turnovers of PFL-AE require methionine and dAdoH replacement with SAM, substrate PFL binding, and the PFL-AE cluster reduction to the 1+ state.
The coexistence of editing and synthetic pathways effectively consumes ATP and converts it to AMP and PPi, while regenerating amino acid and tRNA substrates for the subsequent turnovers.
To provide context for the experimental results reported below, we first point out that the time courses measured for the Ps and Ar 4-HB-CoA thioesterases defined a rapid "burst" of substrate consumption associated with the first catalytic turnover of 4-HB-CoA followed by a slower steady-state rate followed in subsequent turnovers.
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