The doubly and singly protonated forms fold rapidly, and a ϕ-value analysis shows that their contribution to folding occurs subsequent to the transition state ensemble for folding.
16 The TRANxITION trial was conducted to assess the efficacy and tolerance of once-daily NVP-LP 400 mg, subsequent to a transition from an initial twice-daily regime of NVP-IR 200 mg in patients with virologic efficacy.
Subsequent to these pre-transition activities, the transition entails a set of ongoing iterative processes that gradually shift program responsibility from the donor to the program recipient.
In fibroblasts, large Ca transients activate massive endocytosis (MEND) that involves membrane protein palmitoylation subsequent to mitochondrial permeability transition pore (PTP) openings.
Interestingly, the phenotype of frog and fish morphants is relatively late-onset (subsequent to the midblastula transition (MBT) and in most cases after neurulation), which is in contrast to phenotypes associated with knockdown experiments of other proteins linked to DNA methylation such as xDnmt1, xKaiso, and xMBD3 [ 33, 34, 52].
For the pentanoate, fusion was observed at 576 K subsequent to two pre-melting transitions at ca. 206 and 325 K.
Therefore, at high Ca2+, thin filaments freely permit re-attachment of detached crossbridges, allowing them to readily transition between force bearing and non-force bearing states [28] at a rate that is likely limited by transitions subsequent to the Pi isomerization [44].
Using the cut-open oocyte voltage-clamp technique, we found that ArcLight fluorescence likely monitors a protein transition subsequent to gating charge movement, but that accelerating gating kinetics using a previously-reported mutation (Lacroix and Bezanilla, 2012) can nonetheless significantly speed up the fluorescence response.
This phenomenon is ultimately related to a loss of hyperbolicity and to the subsequent transition to ellipticity for the inviscid problem.
While only few nano-molars of fascin are sufficient to induce the transition from asters to stars, the subsequent transition to 'networks' (squares) requires much larger amounts of fascin (several µM; the red curve marks the approximate boundary between the two regions).
In the experiments and calculations, the interaction of a shock wave and an expanding flame front leads to the rapid creation of a turbulent flame brush and, for sufficiently high Mach numbers of the incident shock, to the subsequent transition to a detonation.
