This type of study can often lead to subsequent investigations of the function of the candidate biomarker and hence is called hypothesis generating.
SNPs are single-nucleotide changes within a gene that lead to protein change and subsequent change in the function of that gene.
Given recent efforts to design novel enzymes, the rise of structural genomics and subsequent efforts to predict the function of enzymes from their structure, these units provide a simple framework to describe how nature uses the tools at her disposal, and might help to improve techniques for designing and predicting enzyme function.
Subsequent to the emergence of a new function in one of the duplicates, selection or drift can lead to fixation of that function.
Consequently, the homeostatic regulation of visceral functions subsequent to the decision of whether or not to eat remains largely unexplored.
Additionally future studies must account for covariates, such as renal function, as subsequent to the design of our study, renal impairment was shown to lead to elevated mesothelin levels, which could reduce the accuracy of this assessment [ 36].
We can see that in the long run, the 'bad' receptors may rear up to create subsequent abnormalities in the functioning of several systems that rely on the proper functioning of calcium signaling, such as insulin secretion mechanism, proliferation of parathyroid cells and the development of parathyroid gland hyperplasia in chronic renal failure.
These insights provided the rationale for the subsequent quest toward targeted therapies to repair the function of the aberrant protein.
This effect could arise through the mutations interfering with the function of Rpn12 subsequent to its integration into the proteasome, making it incompatible with the subsequent integration of Rpn10.
Therefore, in the subsequent experiments, we focused on the function of NS1.
In subsequent chapters Nemesius examines the function of the brain, the operation of the senses, imagination, memory, reasoning, and speech; this treatment provided medieval philosophers with a wealth of data from Greek Stoic and other classical empirical philosophers.
