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The dissolution was carried out at different pH condition using 0.1 N HCl (pH 1.2) for 2 h, phthalate buffer (pH 4.5) for next 2 h, and phosphate buffer (pH 6.8) with 4% w/v fresh rat caecal content (RCC) under anaerobic condition for subsequent hours to simulate the GIT condition.
Subsequent to this, we simulated the genotype of individual i at locus l by sampling from a multinomial distribution with parameter f z l l the allele frequency of population z l at locus l (see Figure 1 for a summary of this two-step process).
Next, we used the results to simulate the subsequent course of PSA change and compared the simulation with PSA measurements recorded following measurements in the training set ("validation set").
This is because from a practical stand point the CF profile obtained after the set operation is used as the initial state to simulate the subsequent reset operation.
We numerically demonstrate this effect by solving the Poisson's equation with one SWCNT-bundle bridge the electrode (Fig. 2c, d) and then use this field solution to simulate the subsequent SWCNT-bundles' DEP process.
The same population structure was used to simulate the three subsequent generations (5001 to 5003).
This first interim analysis yielded a PK/PD model which was used to simulate PK and subsequent PD response for a pool of virtual patients for different possible Cohort 2 dose/route combinations.
The discrete cohesive zone model (DCZM) is implemented using the finite element (FE) method to simulate fracture initiation and subsequent growth when material non-linear effects are significant.
Lattice Boltzmann (LB) methods are used to simulate hydrodynamics, reaction and subsequent mass transfer in a disordered packed bed of catalyst particles at sub-pore length-scales.
Saturn V Dynamic Test Vehicle, designated SA-500D, is a prototype Saturn V rocket used by NASA to test the performance of the rocket when vibrated to simulate the shaking which subsequent rockets would experience during launch.
Other ME-model based reconstructions may include a module to simulate plasmid induction and subsequent protein secretion.
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