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Subsequent to prioritising options for service change, an internal working group was formed to consider the feasibility of investment and disinvestment proposals given constraints.
Gould and Vrba (1982) referred to modifications subsequent to co-option of the exapted trait as "secondary adaptations".
"For a year, the university governors have been seeking evidence on the recommendation for reconfiguration of the sector in south east Wales, and the subsequent option to dissolve Cardiff Met," said the university.
Sequential treatment using drug pairs that display CR would, following resistance development, shift the mutant selection window towards higher antimicrobial concentrations, as was previously observed53, and increase the likelihood for resistance development to subsequent treatment options (Fig. 4a).
Key themes emerging from our analysis relate to GPs' definition of LBP, the application of guidelines to individual patients and subsequent treatment options and the way primary care is organized and operates in practice.
A similar situation exists for more indolent conditions, such as CLL and follicular lymphoma, where the decision to initiate treatment and subsequent treatment options may vary with both individual patient and/or clinician choice, as well as with treatment centre.
Among other aspects, the discovery of angiogenesis, the growth of new blood vessels from preexisting vasculature, as a key element in the pathogenesis of malignancy(7) has opened an abundance of biologic insights and subsequent therapeutic options, which have led to improved prognosis in many cancers including those originating from colon, lung, breast, and kidney.
His subsequent options were to a) take a stranger's umbrella, b) walk in the rain, c) wait for the rain to stop, d) contact the police or e) procure a new umbrella through traditional, lawful means.
A subsequent methodological option is to focus on a moment of commencement: a primal scene (Urszene or Anfang) of the research practice that eventually evolved into current synthetic biology discourse.
"Channel 4 have had the opportunity to recommission since 2013, and passed on this and subsequent co-production options put to them.
Therefore, payers have an expanding and obligatory role to ensure that the plan-approved optimal endocrine therapy and subsequent treatment options provided for individual patients with HR+ ABC are evidence based.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com