This theory assigns a logical role for introns in abetting evolution subsequent to their origin, but does not offer a mechanism of their origin.
Thus, genomic instability can be seen as the loss, at the cellular level, of the ability to replicate the genotype with the optimal level of integrity that was gained substantially through evolutionary conditioning subsequent to the origin of the species to which that cell belongs.
Consistent with the ROSG model, the present study may show that the original reason for the gene to be split was the stop-codon interference problem in a random sequence, and that functional sequences may have fortuitously occurred with high probability within these long non-coding introns (and intergenic sequences) subsequent to their origin in random DNA.
For example, species that evolved in allopatry might become sympatric in their distribution subsequent to their origin (e.g., [ 27]).
Because either could have been produced by recombination subsequent to the origin of C11, their occasional occurrence is not informative.
Since sections Repandae and Suaveolentes have diversified to form several species following polyploidization, characters were reconstructed for these sections separately to examine colour evolution subsequent to their origin.
The (erroneous, in our view) implication of several different donor lineages stems merely from the natural workings of LGT among free-living prokaryotes subsequent to the origin of eukaryotes, as sketched in figure 9.
The presence in Africa of A111T only in association with C11 indicates that the observed examples, like those of C3 and C10, resulted from introduction into the continent subsequent to origin.
Previous studies have shown that subsequent to the endosymbiotic origin of mitochondria, a high percentage of the ancestral alpha-proteobacterial protein-coding genes were lost and replaced by proteins of different origins (Gabaldon and Huynen 2003; Gabaldon and Huynen 2007).
The result of LGT among free-living relatives of mitochondria (and chloroplasts) prior to and subsequent to the origins of those organelles is that genes brought in to the eukaryotic lineage by the mitochondrion might now look in a phylogenetic tree as if they had been brought in by a different lineage.
