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An increased risk emerged in subsequent strata of decreasing AFP with decreasing AFSI.
Among RT women, significant excesses were observed for cancers of the oesophagus, stomach, lung, soft tissue sarcomas, thyroid and leukaemias across subsequent strata of age and calendar years at first primary breast cancer.
When the interaction between parity and sexual habits was analysed, the relative risk increased in subsequent strata of parity with increasing number of sexual partners or decreasing age at first intercourse, thus suggesting an independent effect of sexual and reproductive factors, and hence multiplicative on the relative risk of invasive cervical cancer.
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This association has been explored in the present study using different approaches, for IL ALL, AML and MLL status: according to a single weight cut-point, and also exploring the magnitude of association among subsequent birth weight strata.
Drug uptake into, and its subsequent clearance from, the stratum corneum of human volunteers was used to estimate the input rate of diclofenac into the viable skin layers.
Final purification of the radiofolate was achieved using a semi-preparative HPLC system, followed by acidification (pH 1) and subsequent fixation on a Phenomenex Strata X-C cartridge.
Table 4 gives observed and expected numbers of deaths from pleural/peritoneal and lung cancers, and their SMRs, according to age at first and subsequent employment, overall and in strata of sex.
BNPs are readily suspended in water, facilitate adherence to the stratum corneum without subsequent intra-epidermal or follicular penetration, and their interaction with skin is water resistant yet the particles can be removed via active towel drying.
The expected number of subsequent primary cancers in each stratum was obtained by multiplying the sex-, site-, age-, and calendar year-specific incidence rates (rates per person-year) by the related person-years at risk.
Sub-grouping genes by CpG density into more than two strata did not alter subsequent analyses further supporting the dichotomous classification.
The selected model was a generalised linear model for interval censored time to event data [ 24] with different strata for first and subsequent episodes but we also fitted the gap-time Cox model used in an earlier study [ 2].
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