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A gradual increase of diffusivity was observed from RES4 to F3 sample (Figure 5A-D), followed by its decrease for F4 and F5 size fractions (Figure 5E,F), and a subsequent significant increase in last F6 size fraction (Figure 5G).
However, P0 cultures lost the ability to generate tripotent NS, with an approximately 50% reduction from D1 to D14 (Figure 2H) and a subsequent significant increase in the production of NS containing cells of the glial lineage: oligodendrocytes and astrocytes (from 12% to 31%), or astrocytes alone (from 0% to 20%).
Subsequent significant increase reflects upregulated compensatory production within the bone marrow aimed at normalizing the amount of circulating platelets.
These challenges include both the staff and time needed to perform the SST, a well-documented recent (2014) shortage of Synacthen and a subsequent significant increase in Synacthen cost.
Initial successful adoption and the subsequent significant increase in both PCIP access and overall medication transactions over a period of 6 months suggest that the program was easy enough to learn and use.
Table 3 provides an overview of different commonly used scores of organ dysfunction and failure: the Marshall score, the Murray score and the SOFA score all show lowest values in either underweight or normal-weight patients, with a subsequent significant increase in parallel to rising BMI levels.
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Activation of the sorbitol pathway has been seen in 1-month-old rats when subjected to chronic hyperglycemia, leading to reductions in dendritic branching and spine density, and subsequent significant increases in brain sorbitol and inositol, when compared with rats with hypoglycemia (36).
However, in a subsequent study a significant increase in the number of CD4+CD25high T cells was observed after anti-TNF treatment in patients with RA [ 38] who responded to therapy, but not in those patients who failed to respond to therapy.
Subsequent satellite observation showed a significant increase in organization; convective banding cumulatively wrapped around the broad inner-core wind field, and winds gusted to 65 mph (110 km/h).
Subsequent image analysis revealed a significant increase of Jacob-GFP fluorescence in the nucleus within 10 minutes after the last baseline recording (Fig. 2B C).
Subsequent SC-application yields another significant increase by a factor of 10 (p < 0.05).
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