The assumed constant risks of individuals developing CRC would have under- or over-estimated CRC incidence and subsequent resource use for its treatment.
The weight reflects the relative severity of the disease, and subsequent resource use.
A mathematical simulation model of the effects of Prosdex on subsequent resource use and health outcomes will also be developed.
Furthermore, exponential growth of founding populations and subsequent resource competition may prevent other refugial populations from expanding simultaneously [ 4].
The 1-year decision tree was modeled based on clinical events (first and subsequent), resource utilization, and utility data collected in the PLATO trial.
These may be offset by subsequent savings if there is a reduction in failed treatment and less spread of the disease (and therefore less subsequent resource use for retreatment and the treatment of others who become infected).
The relative differences in other costs also combine to make XELOX less costly even when the US data on side-effects and subsequent resource use were modelled together with Hong Kong costs.
These outcomes include whether the initial positive test results or symptoms represented a false positive or whether they served as the first sign of a true recurrence, as well as subsequent resource use for both true and false positives.
In addition to these outcomes, based on these results, a mathematical simulation model of the effects of Prosdex on subsequent resource use and health outcomes will also be developed.
The effects of tobacco, physical exercise, diet and alcohol on morbidity and mortality in industrialised countries, and the subsequent resource investment, largely explain the growing attention being paid by health systems to the promotion of healthy habits and the assessment of their effects [ 1, 2].
The ED conversion rate is increasingly recognised as a key determinant of subsequent resource use [ 1], not least because older people admitted to hospital are at high risk of adverse events [ 2– 4], including long stays, high readmission rates and high rates of long-term care use [ 5, 6].
