Sentence examples for subsequent rational from inspiring English sources

This work paves the way for the first structural study of a membrane bound human sulfatase and subsequent rational design of inhibitors for use as anti-tumor agents.

The analysis of relationships between protein sequences and enzyme characteristics led to the discovery of amino acid residues influencing catalytic properties of cyanobacterial KRs and thus provide the basis for a subsequent rational protein design.

Subsequent rational exploitation of commercially available analogues allowed the identification of activators that are effective at micromolar concentrations and which have an impact on the maximum rate of BtGH84, which the original hit did not.

An advantage of the semi-rational strategy is that rather than being limited by lack of prior knowledge, the results actually contribute information on which genes are important to the phenotype, which facilitates subsequent rational strain modification to achieve further improvement [ 12].

Recent advances in HCV research have provided new opportunities for studying HCV neutralizing antibodies and their subsequent use for rational vaccine design.

Increasing the response rates to ICBs requires insight into the mechanisms underlying resistance and the subsequent design of rational therapeutic combinations on a per patient basis.

In the subsequent Aristotelian tradition of rational mysticism, the spiritual was discovered through meditation on nature.

This was followed in 1688 by a German periodical with an unwieldy title but one that well expressed the intention behind many a subsequent magazine: "Entertaining and Serious, Rational and Unsophisticated Ideas on All Kinds of Agreeable and Useful Books and Subjects".

In this context the models will help on the rational design and subsequent synthesis of new antimycobacterial compounds.

Research in psychology and neuroscience has shown that individual decision-making and subsequent behaviours depend on both rational and non-deliberative, automatic thinking [ 28, 29].

25– 37 Given the aforementioned, to make rational comparisons and subsequent choices between alternative therapies for RA on the basis of economic evidence, the actual prescribed doses in real-life settings must be considered and therapies should be evaluated based on their actual, rather than theoretical cost.