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The compounds were synthesized via successive Suzuki couplings on a suitably functionalized pyridine starting monomer 4 to append phenyl and pyridyl substituents off the 3- and 5-positions, respectively, and then subsequent modifications were made on the flanking pyridyl ring to provide target compounds.
Subsequent modifications were made based on this feedback.
Similar(58)
In subsequent RTOG studies, a number of modifications were made to the radiation treatment.
As subsequent iterations of SearchDOGS were run, modifications were made to improve the initial synteny-determining method, and to improve speed by using BLASTX instead of TBLASTN.
After a pilot workshop with key target and stakeholder groups, modifications were made to this and subsequent workshops based on multisource written observations from interprofessional participants, tutors and an independent educator.
To detect both primary miR-9 transcripts and Hes1 mRNA the following modifications were made to the protocol: EDC fixation was omitted and the temperature of the hybridization + subsequent washes was increased to 65°C.
Modifications were made to the wheels after the incidents.
No modifications were made to this original schematic.
They were not implanted into women once the modifications were made.
After the disaster, the plane was grounded in Britain and France while safety modifications were made.
Dose modifications were made for toxicities.
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CEO of Professional Science Editing for Scientists @ prosciediting.com