Balancing realism against the complexity of the model may promote simpler models, which are beneficial for many subsequent analyses.
no models which are headed for discontinuation.
The third Bond film, Goldfinger, set a pattern for having a main villain with a loyal and dangerous henchman, a model which was followed in subsequent films.
These error measurements were input to the Rosetta error model, which was used for subsequent analysis of statistical significance of differential gene expression.
The main results of Experiment 1 are shown at the end of the paper in Figs. 11 and 12 where they can be interpreted in relation to the modelling which is described in subsequent sections.
In the evaluation process, the SD proportional to the mean model clearly outperforms the proportional to the mean model, which is used in the subsequent analysis.
An alternative model, which is not incompatible with subsequent neofunctionalisation, is the sharing of ancestral functions between gene duplicates (subfunctionalisation), namely partitioning of spatio-temporal expression domains [ 18].
An additive model, which is the default mode in PLINK, fit our data best, and an additive model was therefore chosen for all subsequent analyses.
In subsequent models, in which were successively included diastolic filing of left ventricle, albumin level, and posterior wall thickness only left atrium maintained statistically significant association with PH (relative risk of 1.172; 95% confidence interval of 1.010 – 1.359; p = 0.036).
This indicates that the timing of regulation is less important than the 'wiring' of the system in specifying its dynamical behaviour so we were able to use the less computationally expensive synchronous updates of the model for all subsequent runs which is a useful technical aspect but it implies a much more subtle point.
