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The patient developed extensive radiation pneumonitis, which was treated with high-dose glucocorticoids for 1 year, probably causing a greater rate of bone loss with subsequent insufficiency fracture.
The initial hydrolysis rate (at 4 h) in all of the RS samples was much higher than the subsequent hydrolysis rate, which was consistent with other studies; and selective initial hydrolysis of amorphous cellulose or subsequent insufficiency of new catalytic sites might be the possible explanation for this phenomenon [ 17, 18].
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Of the five patients in the control group, four developed infective complications (three pneumonia, one small bowel perforation related to simultaneous closure of a loop ileostomy) and subsequent hepatic insufficiency as a result of this 'second hit' and one patient developed renal failure requiring haemofiltration, with hepatic insufficiency.
OPG may be directly involved in extraosseous calcification, resulting in stiffening of the arteries and subsequent vascular insufficiency in patients with T1D.
These patients suffered either pituitary haemorrhage in their brain MRI and subsequent hormonal insufficiency or they exhibited symptoms of significant clinical encephalitis based on the criteria of Centers for Disease Control and Prevention CDCC)[ 14].
Many patients report improved symptoms at rest and with elevation of the legs, and some authors have advocated strict avoidance of physical strain as a way to avoid trauma and subsequent impaction or insufficiency fracture of fragile bone [ 10]; our experience corroborates this.
It was shown that severe surgical stress, such as thoracoabdominal surgery, resulted in postoperative relative adrenal insufficiency and subsequent high circulating levels of proinflammatory mediators and development of organ dysfunction [6].
Despite undertaking the precautionary measures, a subsequent study suggested the insufficiency of the deletion of the APOE gene information to prevent a risk prediction for LOAD: "the deletion of the APOE gene information only may not prevent accurate prediction of Dr. Watson's risk for LOAD conveyed by APOE risk alleles.
In one case fetal death of the smaller co-twin occurred at 26 weeks of gestation most likely due to placental insufficiency, with subsequent very preterm delivery of the surviving twin.
Involvement of these structures can lead to hypopituitarism and adrenal insufficiency, and subsequent recovery of their function is rarely seen.
Further investigations revealed exocrine pancreatic insufficiency with subsequent deficiencies of lipophilic vitamins and abnormal clotting parameters and hypothyroidism (Table S4).
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