Subsequent data suggest this occurs via prostaglandin independent mechanisms [ 37], perhaps representing an artefact of ectopic COX-2 expression.
Alternatively, the discrepancy may be attributable to the antibody used by Moreno et al. (1999), which subsequent data suggest may cross-react with d-aspartate oxidase (Shleper et al., 2005), itself abundantly expressed in Golgi and Purkinje cells of the rat (Zaar et al., 2002).
Initial results suggested that caspases-2 and -8 could cleave Bid with similar efficiency [ 42], but subsequent data suggested that the processing by caspase-8 was more efficient [ 43, 44].
While an optimal screening strategy for cervical cancer prevention might involve primary screening by HPV DNA and subsequent cytology, our data suggest that this strategy would need to involve multiple cytology tests to ensure detection of the majority of CIN2+ lesions associated with a positive HR HPV results.
Combining this with the strong epidemiologic evidence linking maternal vitamin D status during pregnancy to subsequent asthma, our data suggest that maternal vitamin D insufficiency may lead to differential developmental regulation of key vitamin D genes within the fetal lung and thus, increase risk of childhood asthma.
However, in subsequent years, data suggested that schistosomiasis has reemerged (7, 9 ).
Because small head size has been found to be predictive of subsequent cognitive ability, these data suggest that chlorpyrifos may have a detrimental effect on fetal neurodevelopment among mothers who exhibit low PON1 activity.
Because of the strong relationship between BMLs and subsequent cartilage loss, these data suggest that weight gain even in young adulthood is detrimental to knee structure and may increase the risk of OA.
NAF-producing ducts are targeted for logistical reasons (NAF allows for the localization of the ductal orifice and subsequent cannulation) and because data suggest that women who produce NAF are at increased risk for the development of breast cancer [ 5].
Finally, delirium increases the risk of subsequent dementia, 13,56,57 but the current data suggest that delirium unmasks an underlying neurodegenerative process rather than creates this neuropathology outright.
The reason for this strain-specific difference in carcinogen sensitivity is not clear, but data suggest involvement of subsequent carcinogenic steps such as tumor promotion rather than the result of differences in carcinogen metabolism [84].
