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A subsequent course of therapy was often ineffective, however, due to neutralising anti-antibody – anti-globulin or human anti-murine (HAMA) – responses [ 9].
31 Hence, the accurate evaluation of virotherapy efficacy at early disease stages may be crucial to making correct decisions about the subsequent course of therapy.
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Objectives: To determine a potential correlation between HIV-specific proliferative responses and the subsequent course of infection under antiretroviral therapy.
After three subsequent courses of GS therapy, no distant metastases were detected under radiological findings.
Emergence of the rtA181T/sW172* mutant in LAM-resistant patients increased the risk of HCC development in the subsequent courses of antiviral therapy.
By analyzing the clinical variables, virological parameters, and clinical use of rescue agents in LAM-resistant mutants, we found older age, cirrhosis, and rtA181T mutation are significantly associated with occurrence of HCC in the subsequent courses of antiviral therapy.
Twenty milliliters of blood were collected into tubes containing EDTA (Greiner Bio-one Vacuette) before starting chemotherapy (baseline) and before administration of each subsequent course of chemotherapy (day 1) until discontinuation of systemic therapy.
One additional resected patient did not have protocol-specified preoperative therapy and was excluded from the resection analysis (considered inoperable after four cycles of chemotherapy, but resected after a subsequent course of chemoradiation).
The subsequent course of the patient was uneventful for a follow up period of 27 months.
Three subsequent courses of GS were administered.
ii) Number of subsequent courses of PEP (self-report and medical record review).
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