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Results suggest that clinical summaries in the U.S. may often be suboptimally designed for communicating important information with patients.
Although generally useful to the clinician, clinical trials have often been suboptimally designed from 1 or several points of view.
These include human resource constraints, weak health systems, and mis-allocation of resources to suboptimally designed or implemented programs.
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The study was designed to determine independent prognostic variables in suboptimally debulked advanced ovarian cancer patients entered in the randomised phase III study EORTC 55865.
The system is designed to address multiple key pathogenetic mechanisms, but most of the key pathogenetic mechanisms are suboptimally affected by this initial system.
This trial was designed to compare the efficacy and safety of denosumab with risedronate over 12 months in postmenopausal women who transitioned from daily or weekly alendronate treatment and were considered to be suboptimally adherent to therapy.
Another trial was designed to compare the efficacy and safety of denosumab with risedronate over 12 months in postmenopausal women who transitioned from daily or weekly alendronate treatment and were considered to be suboptimally adherent to therapy.
We rationally designed these disulfide bonds to manipulate RG13's allosteric regulation mechanism such that the gating had maltose and reducing agents as input signals, and the gates could be toggled between different gating functions using redox agents, although some gates performed suboptimally.
Detailed schematic drawings and representative micrographs provide examples of how best to identify human HF stages, even in suboptimally sectioned tissue, and practical recommendations are given for designing human-on-mouse hair cycle experiments.
We show that solving the open-loop problem suboptimally does not lead to poor closed-loop solutions; instead, suboptimal solutions are corrected through feedback.
To reduce the complexity of PTS-AIC, this paper proposes a suboptimal way, called particle swarm optimization (PSO), to choose the weighting factors suboptimally without much performance degradation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com