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With PPARγ, partial agonists have been demonstrated to facilitate suboptimal positioning of receptor conformations resulting in destabilization of helix H12 distinct from conformations induced with full receptor agonists or antagonists42.
When implementing heating, ventilation and air conditioning systems one should consider aspects like user technology interaction, diverging needs and preferences within group settings, safety issues, and minimising negative behavioural reactions and draught due to suboptimal positioning of outlets.
Given our previous genetic results on interactions between the Ty1 RT polymerase and RNAse H active sites [10], it is plausible that suboptimal positioning of the substrate at the RNAse H active site could influence the conformation at the polymerase active site in ways that disfavor pyrophosphorolysis.
Incorrect or suboptimal positioning was significantly higher in the free-hand cohort as compared to the US guided group (22.3% vs. 5.1% respectively, p=0.005).
Although a suboptimal position of the prosthesis was associated with increased initial migration, this did not influence subsequent stabilization of the prosthesis and a certain degree of suboptimal positioning appears to be tolerated.
These findings could result from asymmetrical dogs' gaits (even with normal hips) [ 38] or from suboptimal positioning of dogs when scoring, but also could be a statistical artefact of identification of QTL with small effects.
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Alternative positions of Xingxiulong were tested to evaluate its suboptimal position.
However, child occupants often assume suboptimal positions during real-world driving trips.
This much more basally suboptimal position of Xingxiulong suggests a high level mosaic evolution around the beginning of basal Massopoda and basal Sauropodiformes.
With two natural first basemen on the roster, Manager Jim Leyland will have to put one of them at a suboptimal position.
It might have been his unwillingness to accept a suboptimal position or Scottish unwillingness to recruit English doctors.
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