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The frequency of emergency department (ED) visits for AD observed in one Midwest urban hospital suggests restricted access to outpatient care and suboptimal maintenance treatment, adding significant cost [ 119].
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This suggests that the molecular mechanism leading to suboptimal telomere maintenance may be distinct for the X-linked and autosomal dominant forms of DC for the mutations we have studied.
Why does anyone receive suboptimal care?
The statistical bias effect leads to suboptimal inspection and maintenance requirements if it is not removed in the corrosion growth analysis.
Multiple factors are perceived to contribute to poor control, including suboptimal adherence to maintenance therapy (4).
Suboptimal adherence to maintenance therapies in asthma [ 3] and COPD [ 4] increases the burden of these diseases on patients and healthcare systems.
Thus, it is not sufficient to consider one of these three events by itself, as it may lead to a suboptimal scheduling of maintenance activities.
Diploid genomes provide a buffer against deleterious effects of mutations and enable the maintenance of suboptimal alleles that could become advantageous if environmental conditions change.
It has not escaped our notice that the appearance of this apparently suboptimal mechanism of telomere maintenance, which might have created chromosome instability, seems to have coincided with the great arthropod radiation into Chelicerata and Mandibulata.
Furthermore, these samples came from areas with suboptimal climate for tick maintenance, i.e., the respective soft ticks are highly resistant to high temperatures and dry conditions, but cold temperatures limit the development of their life cycle, which only starts when the external temperatures are in the range of 10 13 °C [ 18].
We assert that the current 'capture/recapture' pattern maintenance model is suboptimal for adapting patterns to language evolution and propose a new 'capture/modify/recapture' maintenance cycle as a more effective approach.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com