Sentence examples for suboptimal efficacy from inspiring English sources

Currently, medical and surgical treatment options for endometriosis are limited due to suboptimal efficacy, and also safety and tolerance issues.

However, one needs to be cognizant that poor dose regimen design can result in suboptimal efficacy, on-therapy resistance development, and resistance selection that may harm the activity of all β-lactam-β-lactamase inhibitor combinations.

Although their therapeutic potential holds great promise in regenerative medicine applications, translation of growth factors into clinical treatments has been hindered by limitations including poor protein stability, low recombinant expression yield, and suboptimal efficacy.

However, these drugs have major disadvantages, such as long treatment courses, suboptimal efficacy, and/or harmful side effects.

However, delivering recombinant or purified proteins is not ideal due to their short half-lives, suboptimal efficacy, immunogenic potential, batch variabilities, and cost.

Many drugs used in infants are used "off-label", increasing the risk of drug toxicity and suboptimal efficacy in this vulnerable population.

Oftentimes, this heterogeneous drug distribution is one of the primary reasons for suboptimal treatment efficacy in NP delivery platforms.

Although suboptimal pharmacodynamic efficacy, also described as high on-treatment platelet reactivity to ADP, has been associated with greater risk for post-stenting ischemic event occurrence, enhanced responsiveness is associated with higher risk for bleeding in selected patients.

Nelfinavir, which cannot be boosted by ritonavir, is rarely used because of its suboptimal antiviral efficacy.

On this basis, we can therefore hypothesize that the greater antiproteinuric effect of PCT in patients at higher sodium intake could be explained by the suboptimal antiproteinuric efficacy of anti-RAS under these conditions.

This aging-related decline in immune function is termed immunosenescence and is associated with a decreased capacity to induce protective immunity and generate tolerance towards harmless antigens, suboptimal vaccine efficacy and the increased incidence of tumours and autoimmune diseases.