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Cardiomyocytes were transduced and submitted to hypoxic conditions.
This result seems not surprising when considering the decrease in creatine kinase (CK) flux evidenced in hearts of living rats submitted to hypoxic ventilation [28], that could be responsible for an altered energy supply-demand matching.
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Sham animals had their carotids exposed but not occluded nor submitted to the hypoxic atmosphere.
Since expression of CAV1 is upregulated in hypoxic conditions [ 13, 14], mono-cultures were submitted to both hypoxia and normoxia.
Similar alterations of cardiac energetics have already been described not only in isolated heart submitted to reduced O2-supply by decreasing coronary flow or PaO2 in the medium [29], [30], but also in the hypoxic myocardium of living rats [28].
He submitted to daily bloodwork.
We submitted to it completely.
Ephesus soon submitted to Cyrus of Persia.
El Chapo obediently submitted to this scripted choreography.
But I submitted to the tutelage.
There, Neto is submitted to abuse.
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