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All patients submitted to conserving surgery were treated with radiotherapy.
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In our study, one patient (3%) achieved a pCR and 47% of patients were submitted to breast-conserving surgery.
Our results suggest that, after their transfer to the nucleus, these genes have been submitted to a strong selection pressure that conserved them as unique.
Interface membrane samples conserved at -80C were submitted to a procedure described by Nemeth at al. [ 33].
Different PKS or NRPS proteins were submitted to SBSPKS database to modulate and extract conserved domains by Blast search [ 95].
The cap-ring domain (C terminal ∼60 residues) has not been submitted to RosettaDock because, although it is highly conserved, there is no suitable experimentally determined control structure.
Each resulting set of binding sites was submitted to consensus, which is a tool for mining out conserved motifs.
OR = objective response; NR = no response; RS = radical surgery; BCS = breast conserving surgery; NS = not submitted to surgery.
These sequences were submitted to homology search after translation against the NCBI database for identifying conserved domains.
For conserved motif searches, nucleotide sequences (400 bp) centered on each peak were extracted and submitted to the MEME software suite [ 42].
A UN report submitted to Olivier de Schutter, the Special Rapporteur on the Right to Food, highlights: "ecological interventions such as resource conserving and low-input techniques have proven potential to improve yields, on 12.6 million farms globally by 79percentt".
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