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The first area is to support collaboration between researchers, clinicians, patients and carers in the identification of new research questions and the writing of grant applications for submission to research funding bodies.
Trialists should strongly consider soliciting critical appraisal of a proposed RCT by publishing the trial protocol before it is finalized, and prior to its submission to research ethics committees for review.
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Researchers are often hard pressed to come up with coherent accounts of the significance and impact of their work as regularly required in a range of situations, from writing grant proposals to designing implementation strategies and in submissions to research assessment exercises.
Over the past 5 years my role has developed considerably and my responsibilities now include many areas of strategy and policy, from helping to develop the university's research strategy and submission to the research assessment exercise, to drafting policies relating to research ethics and misconduct.
The information regarding the clinical trial is currently being written for submission to a research journal.
Data linkage was performed by SII, and all data were de-identified before submission to the research team.
The data used in this study were extracted from an aggregated anonymised database and submission to a research ethics committee was not required.
The study protocol aimed at developing a PRO instrument should include submission to a clinical research and ethics committee.
The responsible National Health Service (NHS) R&D Consortium stated that this study did not require ethical submission to an NHS research ethics committee as it represented an evaluation of part of an ongoing primary care trust (PCT) programme.
In reviewing submissions to a research ethics board, we have come across sentiments such as So-and-so did a similar study with 6 patients and got statistical significance - ours uses 12 patients (double the size)!
Our experience in reviewing submissions to a research ethics board also shows that most of the pilot projects are not well designed: i.e. there are no clear feasibility objectives; no clear analytic plans; and certainly no clear criteria for success of feasibility.
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