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Figure 1 shows the data flow of the modENCODE DCC pipeline from data submission to data release.
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Supervisors also checked the consistency of data before submission to the data manager.
We consider that the integration of Laboratory Information Management systems (LIMS) and/or Experiment Management Systems (see in this supplement [ 25]) in lab-life operations of omics data, and its standardization (such as the use of ontology-derived nomenclatures) and use in submission to public data repositories will smooth the path towards efficient data discovery and sharing.
Category 3 restrictions prohibit using UMLS-annotated data sets for any of the following purposes: 1) distribution to colleagues, 2) posting on a publicly available site (such as an internet web site), 3) submission to shared data set repositories, or submitted as supplemental data in support of research articles, 4) submission to scientific journals.
The repository is equipped with an online submission interface (electronic data-submission and quick submit) and a paper form submission to insert data.
Though submission to the FAIR Health data is voluntary, there is evidence that the data are nationally representative [7].
The guidelines cover, amongst other topics, the issue of when to release data; for raw sequence data from non-human organisms, the specified deadline is within 6 months of submission to an approved data repository.
Induction of positive controls Arc, Fos and Dusp1 was confirmed by qPCR in the same samples previous to submission to microarrays analysis (data not shown).
Maintenance of biological databases consists of data conversions to accommodate site-specific data formats, and data submission to appropriate sites.
The popularity of the new sequencing methods for gene expression is attested by the numerous recent publications and by the increasing number of submissions to public data repositories such as ArrayExpress (AE) (Parkinson et al., 2008).
We believe that provision of computational services for NGS data analysis without cost to users will increase the use of public data and accelerate data submission to public databases.
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