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Described in this article are strategies implemented to increase the throughput of in vivo rodent pharmacokinetic (PK) studies using the snapshot PK study design and automated methods for compound submission, sample processing, data analysis and reporting.
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Univariable associations between findings of the isolated uropathogens and the three explanatory variables; submission category, sample media (whether the samples were sent in as pre-incubated cultures or not), and if the samples were in pure or contaminated cultures were investigated using Fisher's exact-test, the χ-test and univariable logistic regression analysis.
As a result, any experiments get a unique submission and sample identifier.
Research animal submission, environmental sample, and non-Minnesota animal isolates were excluded.
Practical tools were developed to support data sharing including data submission systems, sample availability systems and standard data access agreements (DAA) for the sharing of individual-level data.
Saskatchewan mule deer samples were provided through hunter submission, and sampling of retropharyngeal lymph nodes was by the University of Saskatchewan and the Canadian Cooperative Wildlife Health Centre during the provincial disease control effort from 2001 to 2007.
In the context of H3Africa projects, the proposal is that ethics committees will approve the submission of samples to the biobank, but what remains unresolved is whether those committees will permit another body (such as a sample access committee or an ethics committee associated with the biobank) to make decisions about appropriate secondary uses of samples.
Passive surveillance is driven by laboratory submission of samples after outbreaks of respiratory disease, whereas active surveillance is based on purposely collecting and screening field samples regardless of clinical status.
Our data indicate the importance of linking patients to care after submission of samples for testing.
Seroprevalence in each subsequent round of testing was artificially skewed toward higher values as a result of selective and repeated submission of samples drawn from previously seropositive hounds.
The success of treatment was monitored using preputial washings into TEM and submission of samples to the diagnostic laboratoryf for Campylobacter spp culture and FAT.
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