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In our workflow, multiple data types from PRCs are submitted to the center using a data submission protocol and standard exchange format, with the metadata using controlled vocabulary whenever possible.
Adhering to the standard submission protocol for data entry, this information should appear in the 'Characteristics column' of ArrayExpress and GEO.
It is also our hope that other groups will want to house their Affymetrix soybean data in SoyXpress, and an online submission protocol is planned.
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The data monitoring team also carry out local quality checks by investigating anomalies in Scottish morbidity records and ensuring that data are amended through usual submission protocols.
We worked closely with staff at WormBase to develop a graphical display of deletion extents in the genome browser, and to streamline data submission protocols to minimize the time between submission and appearance.
Likewise, a clearer policy on the submission of protocol data at the study and experiment level would also avoid confusion.
We also encourage the submission of protocols of general interest and databases.
Several journals have recognised this principle and require submission of protocols with manuscripts.
Chado's structure allows for the easy addition of extensions in the form of new tables, allowing us to extend the schema to accommodate generic submission details, protocols and data references (Supplementary Figure S1).
PW had significant input into the study design; ethics committee submissions and protocol amendments; supervised the conduct of the study on patients at The Great Ormond Street Hospital, London; followed 11 patients that were entered; was the chief investigator of the study; reviewed the results and drafted and finalized the submitted manuscript.
MB, MG and MK were involved in the original design and submission of the protocol for funding and JB reviewed the protocol from a health economics perspective.
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