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Subjects were defined as anemic utilizing the World Health Organization standards [24] for Hgb measured in grams per deciliter (g/dL): less than 12.0 g/dL for women and less than 13.5 g/dL for men.
In the placebo group compliant subjects were defined as those who showed increases of ≤10 nmol/L in folate and ≤150 pmol/L in vitamin B12.
Chronic UTI subjects were defined as a UTI episode within a 12-month time frame or 2 UTIs within 6 months.
IVIG-resistant subjects were defined as KD patients who had persistent fever (≥38.0°C) for at least 36 hours after completion of the IVIG infusion and who received secondary treatment after the initial treatment with IVIG.
Immunosuppressed subjects were defined as those taking at least 10 mg of prednisone daily or other biologic and/or non-biologic immunosuppressive medications (for a complete list of medications represented see Table 2).
In the active treatment group compliant subjects were defined as those who responded with increases from baseline to follow-up in plasma folate of >10 nmol/L and in vitamin B12 of >150 pmol/L.
Subjects were defined as being colonized with cagA+ H. pylori strains if they were positive for CagA antibodies, whether or not they were positive for H. pylori antibodies (CagA+).
Otherwise, subjects were defined as non-smokers.
Prepubertal subjects were defined as age <9 years (21– 21).
GDM and diabetes (for the nonpregnant subjects) were defined as reported (2, 9).
The subjects were defined as obese when their WHR was ≥0.80 [ 10].
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CEO of Professional Science Editing for Scientists @ prosciediting.com